IIT-Kharagpur researchers develop ultra-low-cost system for fast Covid-19 detection

Written by Atri Mitra
| Kolkata |

Updated: July 25, 2020 5:09:33 pm

This ultra-low value system will deliver the testing for Covid-19 out from the partitions of costly laboratories and RT-PCR machines. (Source: IIT Kharagpur)

In a novel effort, researchers at IIT-Kharagpur have developed a first-of-its-kind transportable fast diagnostic system that may detect Covid-19 inside an hour. This ultra-low value system will deliver the testing for Covid-19 out from the partitions of costly laboratories and RT-PCR machines and allow testing at inexpensive prices for the under-served communities the world over.

This take a look at might be carried out for lower than Rs 400 per take a look at, after taking all parts of bills and enterprise mannequin under consideration. The outcomes can then be accessed from a customized smartphone software, with out requiring guide interpretation.

The system is able to conducting the take a look at in an ultra-low-cost transportable enclosure as a substitute for extremely costly RT-PCR machine. The similar transportable unit can be utilized for numerous exams, on mere substitute of the paper cartridge after every take a look at. The design of the brand new system allows its use in areas with extraordinarily poor sources, catering to the wants of the under-served communities. Moreover, it may be operated by minimally-trained personnel, precluding the necessity for expert technicians.

The outcomes can then be accessed from a customized smartphone software, with out requiring guide interpretation. (Source: IIT Kharagpur)

The system has been confirmed to supply no false consequence with outstanding accuracy and sensitivity. The analysis group has efficiently validated the detection process, taking roughly 60 minutes to run every take a look at. While the institute can produce the testing package as much as a sure scale, patent licensing will facilitate commercialisation alternatives for medical expertise corporations.

Prof. Suman Chakraborty from the Mechanical Engineering Department, IIT Kharagpur, and Dr. Arindam Mondal from the School of Bio Science, IIT Kharagpur, got here up with the idea. The expertise primarily deploys a disposable easy paper-strip for chemical evaluation and visualisation of outcomes.

“The distinctive transportable system developed by the IIT Kharagpur researchers has not solely been validated for the diagnostics of Covid-19, but in addition been designed to be able to detecting some other sort of RNA virus by following the identical generic process. The affect of this, due to this fact, is lengthy lasting, empowered by the potential of detecting unexpected viral pandemics within the coming years which will doubtlessly endanger human lives again and again,” stated Dr Mondal.

The challenge acquired monetary help from the institute in late April as Prof. V Okay Tewari, Director, IIT Kharagpur, determined to arrange a fund to help Covid-19 associated analysis and product growth.

(Source: IIT Kharagpur)

“This distinctive innovation is aligned with the Institutional imaginative and prescient to develop high-end healthcare applied sciences that may be afforded by the ailing widespread folks throughout the globe at just about no value, and is prone to make important breakthrough in international viral pandemic administration,” opined Prof. V Okay Tewari.

The Ministry of Human Resources Development (HRD) has additionally been reaching out to all technical establishments concerning ongoing analysis work to assist handle India’s rising want to reinforce testing services.

The outcomes from this new expertise have been strictly validated by following all established laboratory controls in opposition to the benchmarked outcomes obtained from RT-PCR machine, utilizing artificial viral RNA. The artificial RNA is precisely the identical replicate of the viral RNA extracted from contaminated sufferers, as per accepted scientific benchmarking process, and is used for validating laboratory exams to keep away from undue contamination and hazard on account of spreading of an infection whereas dealing with delicate body-fluid samples.

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